CKD Biomarkers Heading

CKD Biomarkers Consortium Laboratory Standard Operating Procedures

Listed below are laboratory SOPs that have been approved by the CKD Biomarkers Consortium Quality Control Committee for use in CKD BioCon Phase II.

Assay SOPs

Procedure Specimen Type Lab
MSD 7-plex protocol for KIM-1, TNFR1, TNFR2, YKL-40, BMP 7, suPAR, MSD Plasma/Urine Brigham and Women’s Hospital: Center for Kidney Diseases
4-plex microbead based assay for KIM-1, YKL-40, EGF, and MCP-1 Urine Brigham and Women’s Hospital: Center for Kidney Diseases
Randox Daytona Creatinine and Phosphorus Urine Brigham and Women’s Hospital: Center for Kidney Diseases

Sample Handling SOPs

Procedure Specimen Type Lab
Aliquoting serum and plasma samples with Metabolomics specific aliquoting plan Plasma/Urine University of Pennsylvania CRIC Central Laboratory
Sample intake, management and data dispatch Plasma/Urine Brigham and Women’s Hospital: Center for Kidney Diseases
Sample aliquoting in the ACRL Plasma/Urine Baylor University Atherosclerosis Clinical Research Laboratory


Please click BioCon I SOP for the approved laboratory SOPs for CKD BioCon Phase I.

bioconpf@pennmedicine.upenn.edu